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Discussion Aging manifests as a heterogeneous process among individuals and across distinct tissues within the same individual

The analysis of the subphenotype revealed that the treatment decreased the number of M2 macrophages that were identified as the profibrotic phenotype (Fig

Hyperglycemic states contribute to cerebral endothelial damage, promote atherosclerosis, affecting cerebral perfusion and function while impeding the clearance of brain metabolites

A recent study has further demonstrated that NIN administration markedly alleviated liver injury and fibrosis by significantly increasing autophagic activity in HSCs, concurrently inducing ferroptosis in mice subjected to BDL (Yu et al., 2024)